non-linear logistic function Search Results


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GraphPad Software Inc non-linear regression analysis and a four-parameter logistic fit function provided by graphpad prism® 5.04 software
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GraphPad Software Inc nonlinear regression 2-parameter logistic function f(x)=1/(1+exp((-eta*(t-t50)
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GraphPad Software Inc non-linear logistic function
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
Non Linear Logistic Function, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Jandel Engineering non-linear curve ¢tting with a logistic function
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
Non Linear Curve ¢Tting With A Logistic Function, supplied by Jandel Engineering, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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GraphPad Software Inc non-linear regression of the sigmoidal dose response function (four-parameter logistic regression)
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
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GraphPad Software Inc unconstrained non-linear regression function (four-parameter logistic equation)
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
Unconstrained Non Linear Regression Function (Four Parameter Logistic Equation), supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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GraphPad Software Inc non-linear regression of dose-response logistic functions
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
Non Linear Regression Of Dose Response Logistic Functions, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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CH Instruments non-linear 4 parameter logistic function
CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, <t>Concentration</t> inhibition <t>curves</t> for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each <t>drug).</t> C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).
Non Linear 4 Parameter Logistic Function, supplied by CH Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, Concentration inhibition curves for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each drug). C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).

Journal: Experimental physiology

Article Title: R-type Ca 2+ channels couple to inhibitory neurotransmission to the longitudinal muscle in the guinea pig ileum

doi: 10.1113/EP086027

Figure Lengend Snippet: CdCl2, ω-CTX but not NiCl2 inhibit IJPs recorded from circular smooth muscle cells. A, IJPs were evoked by a 10 Hz, 1 s stimulus train. These IJPs were blocked by tetrodotoxin (TTX, 0.3 μM) the P2Y1 receptor antagonist, MRS2179 (10 μM) and by the SK channel blocker, apamin (0.1 μM). The stimulus artifacts have been truncated for clarity. B, Concentration inhibition curves for the N-type Ca2+ blocker ω-CTX, and CdCl2 and NiCl2. NiCl2 (up to 50 μM) did not inhibit the IJP (n=4 for each drug). C. Circular muscle IJPs evoked by 5 Hz stimulation are not affected by NiCl2 (50 μM) or NLA (100 μM). D, NiCl2 or NiCl2 plus NLA did not change the amplitude of the single stimuli IJP (n=9). Subsequent addition of apamin (0.1 μM) inhibited the IJP (n=4, *P<0.05 vs. Control).

Article Snippet: Drug concentration response curves were fit using a 4 parameter (max, min, slope, EC 50 ) non-linear logistic function in GraphPad Prism 6.0 (GraphPad Software, Inc., LaJolla, CA).

Techniques: Concentration Assay, Inhibition, Control